How GLP-1 works — in 20 seconds
After a meal, L-cells in your gut release GLP-1. It then:
• Boosts insulin release — only when glucose is high
• Lowers glucagon
• Slows stomach emptying
• Signals fullness in the brain
That's why GLP-1 is one of the most studied peptide hormones today.
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Source:
• Drucker DJ. "Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1." Cell Metabolism, 2018.