Peptide vs steroid — how they signal differently
PEPTIDE HORMONES
• Made of amino acids
• Water-soluble → can't cross the cell membrane
• Bind surface receptors → second messengers (e.g. cAMP) → fast effects
• e.g. insulin, glucagon, growth hormone
STEROID HORMONES
• Made from cholesterol
• Fat-soluble → pass through the membrane
• Bind receptors inside the cell → change gene expression → slower, longer effects
• e.g. testosterone, oestrogen, cortisol
Save 📌 this post.
Follow @peptidesnepal for more info
Visit our website — link in bio for detailed info like this!
Source:
• OpenStax, Anatomy and Physiology 2e — 17.2 "Hormones"